Description
Recombinant full-length human CAMK4 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_001744.
CAMK4 is a multifunctional serine/threonine protein kinase and a member of Ca(2+)/calmodulin-dependent protein kinase family. CAMK4 is localized in neurons in the hippocampus, amygdala, anterior cingulate cortex, somatosensory cortex, and insular cortex (1). CAMK4 is involved in neural activity-dependent signaling in the neuronal nucleus and thought to plays an important role in the consolidation/retention of hippocampus-dependent long-term memory (2)